Scientia Iranica

Scientia Iranica

Nano SbCl5.SiO2: An efficient and heterogeneous catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-one (thione)derivatives under solvent-free conditions

Authors
A. Bamoniri 1
B. F. Mirjalili 2
H. Karbasizadeh 1
1 Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I.R.Iran
2 Department of Chemistry, Faculty of Science, Yazd University, Yazd, I.R.Iran
Abstract
A green approach for efficient and rapid synthesis of biologically active substituted 3,4-dihydropyrimidin-2(1H)-one(thione) derivatives using nano SbCl5.SiO2as a heterogeneous catalyst under solvent-free conditions is reported. The catalyst was characterized by FT-IR, XRD, SEM, TEM and TG-DTG analysis. Compared to the classical reactions, this method consistently has advantages of excellent yields, simple operation, short reaction time, and the avoidance of the use of organic solvents and eco-friendly protocol.
Keywords
Nano SbCl5.SiO2
Heterogeneous acid catalyst
3
4-Dihydropyrimidin-2(1H)-ones(thiones)
solvent-free conditions
Scientia Iranica
Volume 22, Issue 6 - Serial Number 6
Transactions on Chemistry and Chemical Engineering (C)
December 2015
Pages 2332-2340

  • Receive Date 19 May 2015
  • Accept Date 27 July 2017