One-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles using sulfonic acid-functionalized pyridinium chloride as an efficient and recyclable catalyst

Authors

1 Department of Chemistry, University of Sayyed Jamaleddin Asadabadi, Asadabad, 6541835583, Iran

2 Faculty of Chemistry, Bu-Ali Sina University, Hamedan, 6517838683, Iran

3 Department of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran, Iran

Abstract

Sulfonic acid-functionalized pyridinium chloride ionic liquid {[Pyridine–SO3H]Cl} can effectively promote the one-pot multi-component condensation reaction between benzil, aldehydes, primary amines and ammonium acetate under solvent-free conditions at 100 ºC to give the desired 1,2,4,5-tetrasubstituted imidazoles, in high yields and short reaction times.

Keywords

Scientia Iranica
Volume 22, Issue 6 - Serial Number 6
Transactions on Chemistry and Chemical Engineering (C)
December 2015
Pages 2254-2261

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