A green and simple approach toα-acyloxycarboxamides


1 Young Researchers and Elites club, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Department of Chemistry, Science and Research Branch Islamic Azad University, Tehran, Iran


A mild and sustainable three component passerini reaction, in biodegradable deep eutectic solvent based choline chloride:urea (1:2) is described. The reaction proceeds at room temperature involving substituted benzaldehyde, benzoic acid and cyclohexyl isocyanide, with short reaction time and good to excellent yields (65-90%) without tedious workup