Efficient synthesis of highly substituted pyrroles via a multi-component reaction using ZnO nanoparticles as a nanocatalyst

Authors

1 Laboratory of Organic Synthesis and Natural Products, Department of Chemistry, Sharif University of Technology, Tehran, Iran

2 Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran

Abstract

Aconvenient one-pot multi-component reaction of aromatic aldehydes, 1,3-dicarbonyl compounds, amine and nitromethane in the presence of 10 mol % ZnO nanoparticles for the synthesis of highly substituted pyrroles is described. The products were obtained in moderate to good yields via one-pot tandem reaction. This method offers several advantages such as good yields, simple procedure, non hazardous reaction condition and starting from easily accessible substrates.

Keywords


Volume 22, Issue 3 - Serial Number 3
Transactions on Chemistry and Chemical Engineering (C)
June 2015
Pages 948-953
  • Receive Date: 21 January 2015
  • Revise Date: 22 December 2024
  • Accept Date: 27 July 2017