Scientia Iranica

Scientia Iranica

An efficient synthesis of tetrahydrotetrazolo[1,5-a]quinazoline derivatives by a three-component reaction of 5-aminotetrazole, arylaldehydes, and dimedone 

Authors
Department of New Materials, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, PO Box 76315-117, Kerman, Iran
Abstract
A series of tetrahydrotetrazolo[1,5-a]quinazoline derivatives were prepared by the three-component condensation reaction of 5-aminotetrazole (5-AT), benzaldehydes, and dimedone in the presence of p-toluenesulfonic acid (p-TSA) as a solid acid catalyst under solvent-free conditions. This protocol provides a simple one-step procedure with the advantages of easy work-up, mild reaction conditions and environmentally benign.
Keywords

Volume 22, Issue 3 - Serial Number 3
Transactions on Chemistry and Chemical Engineering (C)
June 2015
Pages 942-947

  • Receive Date 11 November 2014
  • Accept Date 27 July 2017