An efficient synthesis of tetrahydrotetrazolo[1,5-a]quinazoline derivatives by a three-component reaction of 5-aminotetrazole, arylaldehydes, and dimedone
Department of New Materials, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, PO Box 76315-117, Kerman, Iran
Abstract
A series of tetrahydrotetrazolo[1,5-a]quinazoline derivatives were prepared by the three-component condensation reaction of 5-aminotetrazole (5-AT), benzaldehydes, and dimedone in the presence of p-toluenesulfonic acid (p-TSA) as a solid acid catalyst under solvent-free conditions. This protocol provides a simple one-step procedure with the advantages of easy work-up, mild reaction conditions and environmentally benign.
Hassankhani, A., & Mosaddegh, E. (2015). An efficient synthesis of tetrahydrotetrazolo[1,5-a]quinazoline derivatives by a three-component reaction of 5-aminotetrazole, arylaldehydes, and dimedone . Scientia Iranica, 22(3), 942-947.
MLA
Asadollah Hassankhani; Elaheh Mosaddegh. "An efficient synthesis of tetrahydrotetrazolo[1,5-a]quinazoline derivatives by a three-component reaction of 5-aminotetrazole, arylaldehydes, and dimedone ". Scientia Iranica, 22, 3, 2015, 942-947.
HARVARD
Hassankhani, A., Mosaddegh, E. (2015). 'An efficient synthesis of tetrahydrotetrazolo[1,5-a]quinazoline derivatives by a three-component reaction of 5-aminotetrazole, arylaldehydes, and dimedone ', Scientia Iranica, 22(3), pp. 942-947.
VANCOUVER
Hassankhani, A., Mosaddegh, E. An efficient synthesis of tetrahydrotetrazolo[1,5-a]quinazoline derivatives by a three-component reaction of 5-aminotetrazole, arylaldehydes, and dimedone . Scientia Iranica, 2015; 22(3): 942-947.
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