Scientia Iranica

Scientia Iranica

Fe2+supported on hydroxyapatite-core-shell-γ-Fe2O3nanoparticles: As a novel, efficient and magnetically-recoverable catalyst for the synthesis of dihydropyrimidinones derivatives

Authors
Eshagh Rezaee Nezhad 1
Zahra Abbasi 2
Sami Sajjadifar 3
1 1Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran
2 Young Researchers and Elite club, Ilam Branch, Islamic Azad University, Ilam, Iran
3 Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran
Abstract
Fe2+supported on hydroxyapatite- core-shell magnetic γ-Fe2O3 nanoparticles (γ-Fe2O3@HAp-Fe2+ NPs) is reported as a novel, efficient, reusable and heterogeneous catalyst. In this protocol, we used this catalyst for the synthesis of 4-dihydropyrimidin-2(1H)-ones/thiones in good to high yields by the reaction of aromatic aldehyde, β-dicarbonyl and urea/thiourea under solvent free condition.The catalyst can be readily isolated by using an external magnet and no obvious loss of activity was observed when the catalyst was reused in seven consecutive runs. The mean size and the surface morphology of the nanoparticles were characterized by TEM, SEM, VSM, XRD and FTIR techniques.
Keywords
magnetic nanoparticles
Heterogeneous catalyst
Solvent-free
Biginelli reaction
Fe2+ supported
Scientia Iranica
Volume 22, Issue 3 - Serial Number 3
Transactions on Chemistry and Chemical Engineering (C)
June 2015
Pages 903-910

  • Receive Date 11 November 2014
  • Accept Date 27 July 2017