Scientia Iranica

Scientia Iranica

Synthesis of 1, 4-dihydropyridines (DHP) Catalyzed by Trichloroisocyanuric Acid (TCCA) in Aqueous Media

Authors
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Abstract
An array of 1, 4-dihydropyridines (DHP) derivativeswas synthesized by Hantzsch three-component reaction of aromatic aldehydes, ethyl acetoacetate and ammonium acetate using trichloroisocyanuric acid (TCCA) as an efficient catalyst in aqueous media. The proposed method was operationally simple and to make the process benign for the environment, water used as a reaction medium. No aromatization of dihydropyridinesproducts was done in the presence of TCCA as an oxidant.
Keywords

Volume 23, Issue 6 - Serial Number 6
Transactions on Chemistry and Chemical Engineering (C)
December 2016
Pages 2756-2761

  • Receive Date 15 November 2015
  • Accept Date 27 July 2017