A novel un-catalyzed and solvent-free method for the synthesis of 2-thioxothiazolidin-4-ones

Authors

Department of Chemistry, School of Science, Alzahra University, PO Box 1993891176, Vanak, Tehran, Iran

Abstract

An easy and highly efficient one-pot, three-component synthesis of rhodanines is reported. The reaction of primary amines, carbon disulfide and chloroacetyl chloride proceeded in the absence of solvent and catalyst, to afford 2-thioxothiazolidin-4-ones in good to excellent yields.

Keywords


Volume 21, Issue 3
Transactions on Chemistry and Chemical Engineering (C)
June 2014
Pages 748-751
  • Receive Date: 05 August 2013
  • Revise Date:
  • Accept Date: 27 July 2017