A novel un-catalyzed and solvent-free method for the synthesis of 2-thioxothiazolidin-4-ones

Authors

Department of Chemistry, School of Science, Alzahra University, PO Box 1993891176, Vanak, Tehran, Iran

Abstract

An easy and highly efficient one-pot, three-component synthesis of rhodanines is reported. The reaction of primary amines, carbon disulfide and chloroacetyl chloride proceeded in the absence of solvent and catalyst, to afford 2-thioxothiazolidin-4-ones in good to excellent yields.

Keywords