A facile and green three-component synthesis of 2-amino-3-cyano-7-hydroxy-‎‎4H-chromenes on grinding

Authors

Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran‎

Abstract

A simple, efficient and one-pot method has been developed for the synthesis of densely functionalized aryl derivatives of 2-amino-3-cyano-7-hydroxy-4H-chromene by the domino Knoevenagel-Michael-cyclization reactions of aromatic aldehydes, resorcinol and malononitrile in the presence of a catalytic amount of Na2CO3 under grinding conditions.

Keywords


Volume 21, Issue 3
Transactions on Chemistry and Chemical Engineering (C)
June 2014
Pages 742-747
  • Receive Date: 11 November 2013
  • Revise Date: 21 December 2024
  • Accept Date: 27 July 2017