1
Department of Chemistry,Sharif University of Technology
2
Department of Chemistry,University of Leeds
3
Department of Chemistry,University of Kerman
Abstract
A sensitive colorimetric method for the detection of ascorbic acid was proposed in this
research based on the reduction of silver ions by ascorbic acid in the presence of citrate-stabilized silver
seeds, additional trisodium citrate and a polymer such as polyvinylpyrrolidone. The color of the stable sol
is controlled by varying the concentration of trisodium citrate (TSC), polyvinylpyrrolidone, silver nitrate
and silver seeds. The reduction of Ag+ to triangle silver nanoparticles (Ag-NPs) by ascorbic acid in the
presence of trisodium citrate (TSC) and silver seeds produced two very intense surface plasmon resonance
peaks of Ag-NPs. The plasmon absorbance of Ag-NPs allows the quantitative spectrophotometric detection
of the ascorbic acid. The calibration curve derived from the changes in absorbance at = 427 nm was
linear, with the concentration of ascorbic acid in the range of 6:010????6 to 8:010????5 M. The method was
applied to the determination of ascorbic acid in pharmaceutical formulations with satisfactory results.
Hormozi Nezhad, M. R., Karimi, M., & Shahheydari, F. (2010). A Sensitive Colorimetric Detection of Ascorbic Acid in Pharmaceutical Products Based on Formation of Anisotropic Silver Nanoparticles. Scientia Iranica, 17(2), -.
MLA
Mohammad Reza Hormozi Nezhad; M.A. Karimi; Fatemeh Shahheydari. "A Sensitive Colorimetric Detection of Ascorbic Acid in Pharmaceutical Products Based on Formation of Anisotropic Silver Nanoparticles". Scientia Iranica, 17, 2, 2010, -.
HARVARD
Hormozi Nezhad, M. R., Karimi, M., Shahheydari, F. (2010). 'A Sensitive Colorimetric Detection of Ascorbic Acid in Pharmaceutical Products Based on Formation of Anisotropic Silver Nanoparticles', Scientia Iranica, 17(2), pp. -.
VANCOUVER
Hormozi Nezhad, M. R., Karimi, M., Shahheydari, F. A Sensitive Colorimetric Detection of Ascorbic Acid in Pharmaceutical Products Based on Formation of Anisotropic Silver Nanoparticles. Scientia Iranica, 2010; 17(2): -.
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