A Simple Access to the Synthesis of 5,6- Dihydro-4H-1,3-oxazines Under Solvent Free Condition and Microwave Irradiation

Authors

Department of Chemistry,Guilan University

Abstract

2-Arylsubstituted 5,6-dihydro-4H-1,3-oxazines were conveniently synthesized by the condensation of 3-aminopropanol and desired carboxylic acids under solvent free and microwave conditions in short reaction times with moderate to good yields. A comparison of this method with the classical protocols using acid halides and nitrile substrates was also made.

Volume 16, Issue 1 - Serial Number 1
Transactions on Chemistry and Chemical Engineering (C)
June 2009
  • Receive Date: 29 June 2009
  • Revise Date: 21 December 2024
  • Accept Date: 29 June 2009