A Novel Synthesis of 2-(Alkylamino) and 2-(Arylamino)- 4(3H) Quinazolinones by Heterotrocyclization of 2-Aminobenzamide with Isothiocyanates (or Isocyanates) under Microwave Irradiation
Department of Chemistry,Ferdowsi University of Mashhad
Abstract
A convenient one-pot preparation of 2-(alkylamino) and 2(arylamino)-4(3H) quinazolinones in high yields has been developed by microwave induced heterocyclization of 2-aminobenzamide with isothiocyanates (or Isocyanates) in solvent-free conditions. In comparison, the reactions are faster under microwave irradiation and the yields are much higher than those by/of conventional heating (under reflux in toluene).
Tavallaii, Z. (2007). A Novel Synthesis of 2-(Alkylamino) and 2-(Arylamino)- 4(3H) Quinazolinones by Heterotrocyclization of 2-Aminobenzamide with Isothiocyanates (or Isocyanates) under Microwave Irradiation. Scientia Iranica, 14(4), -.
MLA
Z. Tavallaii. "A Novel Synthesis of 2-(Alkylamino) and 2-(Arylamino)- 4(3H) Quinazolinones by Heterotrocyclization of 2-Aminobenzamide with Isothiocyanates (or Isocyanates) under Microwave Irradiation". Scientia Iranica, 14, 4, 2007, -.
HARVARD
Tavallaii, Z. (2007). 'A Novel Synthesis of 2-(Alkylamino) and 2-(Arylamino)- 4(3H) Quinazolinones by Heterotrocyclization of 2-Aminobenzamide with Isothiocyanates (or Isocyanates) under Microwave Irradiation', Scientia Iranica, 14(4), pp. -.
VANCOUVER
Tavallaii, Z. A Novel Synthesis of 2-(Alkylamino) and 2-(Arylamino)- 4(3H) Quinazolinones by Heterotrocyclization of 2-Aminobenzamide with Isothiocyanates (or Isocyanates) under Microwave Irradiation. Scientia Iranica, 2007; 14(4): -.
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