Zinc leaching residue, a bulk solid waste from non-ferrous industries, is produced in excess of 6 million tons annually in China. Exploring effective treatment and resource utilization technologies for zinc leaching residue has become an important topic in the field of environmental engineering. In this study, zinc leaching residue was first desulfurized to improve its suitability as a cement admixture. Subsequently, the desulfurization products were reduced, and the effects of reduction conditions on the reduction rates of zinc, iron and lead were systematically studied. Finally, the properties of cement prepared using zinc leaching residue reduction slag as cement admixture were analyzed. Research has found that a desulfurization rate of more than 95% can be achieved at 1300 °C and a holding time of 10 min. Under the conditions of 1350 °C, 40 min of holding time and a calcium-to-silicon ratio of 0.8, the reduction rates of iron, zinc and lead all reached over 97%. Using zinc leaching residue reduction slag as cement admixture, with appropriate addition amount, the prepared cement meets industry standards. This article provides insights into the co-production of cement from bulk solid waste in the non-ferrous metal industry.