How can we measure the slowing down of healthy and ischemic stroke individuals?

Document Type : Article


1 Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, 15875-4413, Iran

2 Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

3 Nonlinear Systems and Applications, Faculty of Electrical and Electronics Engineering, Ton Duc Thang University, Ho Chi Minh City, Vietnam


Recently, resilience has attracted lots of attention in the study of biological systems. The goal of this paper is investigating the slowness in ischemic stroke patients. A Trier Social Stress Test (TSST) is used to reveal the slowness of the biological system. The slowness of dynamics is calculated for the ECG of healthy individuals and patients with ischemic stroke. The ECG is investigated in four stages: before stress, right after stress, 20 minutes after stress, and 40 minutes after stress. Ten healthy individuals and nine ischemic stroke patients are studied. Six early warning indicators based on slowness and variability are used in this study. The indicators are applied to the RR interval of individuals in four stages. Also, the results were normalized with the rest state of each individual. Heart rate variations were studied as another measure of the slowness of the dynamics. The results reveal that there is no significant difference in the slowness of healthy and patient cases. So, in this case, resilience cannot be used in predicting health problems.


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