MCM-41-SO3H-catalyzed synthesis of highly substituted 3-amino-imidazo[1,2-a]pyridines or pyrazines via the Groebke-Blackburn-Bienaymé multicomponent reaction under grinding conditions at ambient temperature

Authors

Abstract

Environmentally-friendly and highly efficient method has been developed by a sequential one-pot, three-component reaction between isocyanides, aldehydes and 2-aminopyridines or 2 aminopyrazines under solvent-free and grinding- conditions at room temperature in the presence of nano-ordered MCM-41-SO3H.

Keywords


Volume 23, Issue 6 - Serial Number 6
Transactions on Chemistry and Chemical Engineering (C)
December 2016
Pages 2724-2734
  • Receive Date: 15 November 2015
  • Revise Date: 21 December 2024
  • Accept Date: 27 July 2017