One-pot solvent-free synthesis of pyranonaphthoquinone-fused spirooxindoles catalyzed by SBA-IL

Document Type : Article


1 Department of Chemistry, Alzahra University, P.O. Box 1993891176, Tehran, Iran

2 School of Chemistry, College of Science, University of Tehran, 14155-6455, Tehran, Iran


In this research article, ionic liquid modified SBA-15 mesoporous material (SBA-IL) as a recyclable, heterogeneous catalyst efficiently catalyzed the synthesis of pyranonaphthoquinone-fused spirooxindoles through the one-pot three-component reaction of isatin derivatives, activated methylene reagents, and 2-hydroxy-1,4-naphthoquinone. The reactions were performed under microwave irradiation and solvent-free conditions. The synthesized SBA-IL was characterized by SEM, FT-IR, nitrogen adsorption-desorption, and thermogravimetric analyses. Excellent chemical yields, short reaction times, mild reaction condition, easy workup procedures and reusability of catalyst are noteworthy advantages of this protocol.


Main Subjects

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