Sharif University of Technology Scientia Iranica 1026-3098 20 6 2013 12 01 Synthesis of 2-amino-4,6-diarylnicotininitriles using 3-propyldiethylenetriamine-silica as a recyclable solid base catalyst Synthesis of 2-amino-4,6-diarylnicotininitriles using 3-propyldiethylenetriamine-silica as a recyclable solid base catalyst 1863 1870 3428 EN Khodabakhsh Niknam Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran Reza Rashidian Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran Abbas Jamali Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran Journal Article 2013 08 03 A simple and efficient procedure for the preparation of 3-propyldiethylenetriaminesilica (PDTAS) by reaction of 3-chloropropylsilica with diethylene-triamine is described. 3-Propyldiethylenetriaminesilicais employed as a recyclable base catalyst for the synthesis of 2-amino-4,6-diarylnicotininitrilefrom the reaction of acetophenone derivatives, aromatic aldehydes, malononitrile, and ammonium acetate under solvent-free conditions at 100 oC. The heterogeneous solid base catalyst was recycled for four runs upon the reaction of 4-chloroacetophenone, 4-chloroenzaldehyde, malononitrile, and ammonium acetate without losing its catalytic activity. https://scientiairanica.sharif.edu/article_3428_44c4cec1643f45fb144853c3434a64dc.pdf