Sharif University of Technology Scientia Iranica 1026-3098 16 2 2009 12 01 Production of Chitosan by Submerged Fermentation from Aspergillus niger 3269 EN S. Yaghmaei Department of Chemical and Petrochemical Engineering,Sharif University of Technology V. Maghsoodi Biochemical and Bioenvironmental Research Center,Sharif University of Technology J. Razavi Biochemical and Bioenvironmental Research Center,Sharif University of Technology Journal Article 2010 05 12 The eect of glucose concentration in submerged fermentation (SMF) on chitosan production by Aspergillus niger was investigated. A. niger, BBRC, 20004, from the Biochemical and Bioenvironmental Research Centre at Sharif University of Technology, Tehran, Iran, was grown in a Sabouro Dextrose media. Chitosan was extracted from the fungal mycelia using hot alkaline and acid treatment and after 12 days of cultivation, 0.8455 g chitosan /l of the fermentation medium was obtained. The content of glucose in the Sobouro Dextrose Broth media was also changed and the highest yield of chitosan 0.9121g/l was obtained in Sobouro Dextrose Broth media containing 8% glucose. https://scientiairanica.sharif.edu/article_3269_c74b21e07952f940b51d9c438555406a.pdf