Sharif University of Technology Scientia Iranica 1026-3098 31 9 2024 06 01 Effects of the microchannel shape upon droplet formations during synthesis of nanoparticles 727 736 23293 10.24200/sci.2023.60984.7089 EN F. Raji Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran. 0000-0003-2098-3983 M. Kazemeini Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran. 0000-0001-5681-962X Journal Article 2022 08 18 Advances in nanotechnology has made it possible to produce minimal tools and equipment that can be used to control tiny volumes of fluids. Such systems, currently at the center of attention of scientists in various fields, are referred to as microfluidic systems. also, the ability to synthesize nanoparticles with precise control over particle’s form and size is crucial. The major goal of this research was to see if the nozzle-focused microchannels could have been used to synthesize the Polycaprolactone (PCL) polymer nanoparticles through the COMSOL Multiphysics 5.4 software medium. In this study, the static velocity and pressure of the droplet after leaving the nozzle and entering the main channel, as well as the size, shape, distribution, and weight of the droplet in terms of the time step, were understudied. It was revealed the channel design was such that, the droplets could have maintained their stable shape at the end of it. Finally, it was shown that, the droplet possessed a dual functionality of place and time in terms of the size and weight distribution after a time step of 0.00305 seconds. The maximum drop saturation mass was formed, and the droplet diameter size displayed a plateau after 0.01 seconds. https://scientiairanica.sharif.edu/article_23293_2bc16f61719c604450e92d898ed19585.pdf