TY - JOUR ID - 3659 TI - Na+ permeation through its protein channels, from molecular dynamics to continuum modeling JO - Scientia Iranica JA - SCI LA - en SN - 1026-3098 AU - Rismanian, M. AU - Saidi, M.S. AU - Firoozabadi, B. AD - Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran AD - Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran. Y1 - 2015 PY - 2015 VL - 22 IS - 2 SP - 459 EP - 466 KW - Protein channel KW - Forward-reverse constant velocity steered molecular dynamics KW - Multiscale mass transport KW - Langevin dynamic equation KW - Na+ DO - N2 - Researchers can reach important information about cell cycles such as migration, growth and muscle contraction, by studying the change of ion concentrations in animal cells. In the current work we have proposed three di erent techniques to study the passive ions motion in protein channels on di erent time scales. Molecular dynamics, Langevin dynamics and continuum models of mass transport are used to investigate ion transport from small to large time scales...................... UR - https://scientiairanica.sharif.edu/article_3659.html L1 - https://scientiairanica.sharif.edu/article_3659_615d6c8214534c9f8900090dfcb3be7e.pdf ER -