TY - JOUR ID - 20491 TI - A multi-component reaction for the direct access to 4,4'-(phenylmethylene)bis(1H-pyrazol-5-ol)-3-carboxylates using nano-NiZr4(PO4)6 in water JO - Scientia Iranica JA - SCI LA - en SN - 1026-3098 AU - Safaei-Ghomi, Javad AU - Shahbazi-Alavi, Hossein AU - Ziarati, Abolfazl AD - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, I. R. Iran AD - School of Chemistry, College of Science, University of Tehran, Tehran 14155-6455, Iran Y1 - 2018 PY - 2018 VL - 25 IS - 6 SP - 3288 EP - 3294 KW - Multi-component KW - Water KW - Pyrazole KW - Catalyst KW - One-pot KW - Nano-NiZr4(PO4)6 DO - 10.24200/sci.2018.20491 N2 - An efficient synthesis of 4,4'-(phenylmethylene)bis(1H-pyrazol-5-ol)-3-carboxylates is achieved by one pot pseudo five-component reaction of phenylhydrazine, acetylenedicarboxylates and aromatic aldehydes in the presence ofnano-NiZr4(PO4)6 at 60°C in water. Nano-NiZr4(PO4)6  has been characterized by powder X-ray diffraction (XRD) and scanning electronic microscopy (SEM). Use of simple and readily available starting materials, excellent yields in short times, reusability of the catalyst, little catalyst loading and simple operational procedures are some of the important features of this protocol. UR - https://scientiairanica.sharif.edu/article_20491.html L1 - https://scientiairanica.sharif.edu/article_20491_8140dbac7ad613b411bef10fa81888bf.pdf ER -