In this paper, the effect of the combustion and turbulence sub-grid scale (SGS) model on the simulation of pool fire turbulence field has been studied in open source CFD software, OpenFOAM. Two combustion models of Eddy Dissipation Model (EDM) and infinite fast chemistry, with the one-equation and Smagorinsky SGS model, is evaluated for a large-scale pool fire. In general, fast kinetic-based combustion models predict excessive heat release rate. The mean squared of the velocity fluctuations is over-predicted. In this simulation, the turbulence models have no significant effect on the results. In fact, the effect of the combustion model is dominant. The EDM combustion model is more compatible when used with the one-equation SGS model and improves the results compared to other cases. In addition, the infinite fast chemistry combustion model is not a suitable model for fire simulation.