@article { author = {Safaei-Ghomi, Javad and Shahbazi-Alavi, Hossein and Ziarati, Abolfazl}, title = {A multi-component reaction for the direct access to 4,4'-(phenylmethylene)bis(1H-pyrazol-5-ol)-3-carboxylates using nano-NiZr4(PO4)6 in water}, journal = {Scientia Iranica}, volume = {25}, number = {6}, pages = {3288-3294}, year = {2018}, publisher = {Sharif University of Technology}, issn = {1026-3098}, eissn = {2345-3605}, doi = {10.24200/sci.2018.20491}, abstract = {An efficient synthesis of 4,4'-(phenylmethylene)bis(1H-pyrazol-5-ol)-3-carboxylates is achieved by one pot pseudo five-component reaction of phenylhydrazine, acetylenedicarboxylates and aromatic aldehydes in the presence ofnano-NiZr4(PO4)6 at 60°C in water. Nano-NiZr4(PO4)6  has been characterized by powder X-ray diffraction (XRD) and scanning electronic microscopy (SEM). Use of simple and readily available starting materials, excellent yields in short times, reusability of the catalyst, little catalyst loading and simple operational procedures are some of the important features of this protocol.}, keywords = {Multi-component,Water,Pyrazole,Catalyst,One-pot,Nano-NiZr4(PO4)6}, url = {https://scientiairanica.sharif.edu/article_20491.html}, eprint = {https://scientiairanica.sharif.edu/article_20491_8140dbac7ad613b411bef10fa81888bf.pdf} }